Endocrine Abstracts

Introduction: Acromegaly is a relatively uncommon disease and is frequently associated with thyroid diseases whose risk increases with the age of the disease.

Objective: The purpose of our study was to determine the different thyroid abnormalities observed during acromegaly to improve their management.

Patients and methods: Retrospective, descriptive study involving 43 acromegalic patients hospitalized at the Department of Endocrinology, Diabetology and Metabolic Diseases CHU IBN ROCHD, Casablanca from January 2005 to December 2018. All patients underwent morphological and functional exploration of the thyroid.

Results: The meanage of our patients was 48 years (13–73), with sex ratio H / F: 0.53 and a diagnostic delay of 4 years. Goiter was present in 74.4% of cases, of which 16.2% had nodular goiter and 58.1% had multi-heteronodulargoitre. Thyrotropic insufficiency was observed in 32.5%. No cases of primary hyperthyroidism have been reported. And one case of papillary thyroid carcinoma was diagnosed inone patient.

Conclusion: The elevation of the IGF1 level plays a major role in the pathophysiology of thyroid disorders, hence the need for systematic morphological and functional exploration of the thyroid during the discovery of acromegaly and surveillance. regular and possible cytopraction of suspicious nodules is necessary in order to watch for thyroid abnormalities that may appear during the evolution of the disease.