Endocrine Abstracts

A 19 year old Bangladeshi male attended ED with a fractured finger. He was noted to have a severely delayed bone age of 13.5 years, and no facial hair. He had moved to the UK aged 11 and could recall little information regarding his childhood or his parents. He had no significant medical co-morbidities, and in particular no history of mumps, measles or testicular injury. He reported being the shortest in his class, and being unable to keep up with his classmates in physical ac...

A 16 year old boy presented to his GP with a two month history of polyuria and polydipsia. He was reviewed by his GP and diabetes mellitus was ruled out. At the time of presentation three months later, he had a three week history of headache and vomiting. His glasses prescription had changed and he had increasing diplopia. The optician found bilateral papilloedema and he was referred to the eye clinic for further assessment. Due to abnormal gaze palsies, he was admitted to the...

Background: Hamartoma of the hypothalamus represents a well-known but rare cause of central precocious puberty and gelastic epilepsy. Due to the delicate site in which a tumour is located, surgery is often difficult and associated with considerable risks.History: 10-year old girl presented with early menstrual cycles. The condition started at age of one year when her parents noticed that their child has developed abnormal vaginal bleeding. Her cycles wer...