Endocrine Abstracts

We retrospectively studied the effect on BMI and metabolic control (HbA1c within therapeutic targets) of structured lifestyle intervention associated with glucagon-like-1 receptor agonists (GLP-1RA) compared to GLP-1RA alone in patients with Type 2 diabetes (T2DM).Materials and method: The anthropometric and clinical data of 525 T2DM patients who started therapy with GLP-1RA were collected in a comprehensive database with follow-up of 24 months. Accordin...

Introduction: Increasing evidence shows that type 2 diabetes mellitus (T2DM) could be reversible and that this is related to weight loss. Significant weight loss achieved through bariatric surgery or medically can result in diabetes remission. Diabetes remission is more likely to occur in those who are younger, have shorter duration of disease, and are on fewer diabetes medications. The impact of using a low energy formula-based diet in combination with physical activity on T2...

Introduction: Slimming World on Referral (SWoR) is a well-established partnership with NHS and local government commissioners, which provides a cost-effective, 12-week, tier-2 weight management intervention for patients, some of whom may meet NICE criteria for tier 3 services. This analysis examines weight loss outcomes by baseline BMI at 3, 6 and 12 months.Methods: Referrals to Slimming World were made through 80 locally-commissioned schemes across Engl...

Objective: To evaluate the chance of developing new cases of Type 2 diabetes mellitus (DM) in obese people in the population sample of the city of Novosibirsk aged 45–69 years.Materials and methods: The analysis included 2464 people, including 586 (23.7%) men and 1878 (76.2%) women without DM. This sample was formed from the base of the international project HAPIEE surveyed from 2003 to 2005. When conducting a re-screening of the same sample in 2006...