Endocrine Abstracts

Background: Congenital hyperinsulinism (CHI) is one of the commonest causes of recurrent hypoglycaemia due to excess production of insulin in infancy and results in neurological impairment in a third to a half of patients. The treatment of CHI is often complex and complicated by side effects; the medium-term effects of such treatment are not known.Aim: To describe five year clinical outcomes in a cohort of infants with CHI.Methods:...

Background/Aims: More young people with gender dysphoria are undergoing hormonal intervention with GnRHa treatment. The impact on bone density is not known in the very young transgender adolescents, with guidelines mentioning that Bone Mineral Density (BMD) should be monitored without a suggestion on how. This study aimed to investigate whether there were any changes in BMD or Bone Mineral Apparent Density (BMAD) whilst on GnRHa therapy.Methods: A retros...

Introduction: Utilization rates of fertility preservation among transgender adolescents (TA) are low. Few studies have addressed the reproductive desires of this population. The aim of this study was to assess TA parenthood goals, attitudes about fertility preservation (FP) and perceived barriers to successful gamete banking.Methods: Transgender adolescents who attended the Gender Identity Development Service (GIDS - endocrine clinic) between March and J...