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Belgian Endocrine Society 2018

BES 2018

Vegf-A mRNA transfection as a novel approach to improve mouse and human islet graft revascularization

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The accuracy of self-reported fractures among a Belgian cohort of postmenopausal women: The FRISBEE study

ea0057008 | Vegf-A mRNA transfection as a novel approach to improve mouse and human islet graft revascularization | BES2018

Vegf-A mRNA transfection as a novel approach to improve mouse and human islet graft revascularization

Willem Staels , Yannick Verdonck , Yves Heremans , Gunter Leuckx , Sofie De Groef , Carlo Heirman , Eelco de Koning , Conny Gysemans , Kris Thielemans , Luc Baeyens , Harry Heimberg , Nico De Leu

Aims/hypothesis: The initial avascular period following islet transplantation seriously compromises graft function and survival. Enhancing graft revascularization to improve engraftment has been attempted through virus-based delivery of angiogenic triggers, but risks associated with viral vectors have hampered clinical translation. In vitro transcribed mRNA transfection circumvents these risks and may be used for improving islet engraftment.Meth...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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