Endocrine Abstracts

Background: Despite the efforts to reduce smoking, unfortunately there is a common belief in society to avoid smoking cessation or quitting smoking for weight control. As well as many negative effects of smoking, people continue to smoke instead of diet and life change. Nicotine plus high fat diet (HFD) induces intramyocellular lipid accumulation and mitochondrial abnormalities in obese mice. There is limited data in the relation of dietary fat content and metabolic syndrome in Turkish smoker population.

Objectives: Therefore the aim of the study is to investigate the relationship between dietary fat content and anthropometric measurements for smokers and non-smokers; as well as the effects of smoking and dietary fat content on obesity, metabolic syndrome.

Methods: In total 211 participants 104 smoker,107 non smoker were included in this prospective cross-sectional study. Venous blood samples were collected after a 12h fasting to determine glucose, high-density lipoprotein (HDL-c), and triglyceride levels. Anthropometric measurements and resting blood pressure were also evaluated. Food consumption was assessed through the 24-hour dietary recall method, and the amount of fat consumed by a single dietician is calculated as low or high. Metabolic syndrome was defined according to the International Diabetes Federation definition guidelines.

Results: There was no relationship between smokers and non-smokers anthropometric parameters except hip circumference. Hip circumference of the non-smokers were statistically higher than smokers (P=0.02). HFD and metabolic syndrome were not statistically important both of smokers and non-smokers (P=0.21 and P=0.48). In non-smokers high fat diet induces poor glycemic control (P=0.20). There was no relationship between dietery fat content and non alcoholic fatty liver disease in smokers and non-smokers (P=0.07 and P=0.18).

Conclusion: We observed that smoking reduced only the hip circumference in smokers. But there is widespread belief that smoking has a positive effect on weight in the community. Smokers did not show improvement in weight control and obesity-related metabolic values. We observed that dietary fat content was not associated with smoking and the metabolic syndrome.