ECE2018 Poster Presentations: Diabetes, Obesity and Metabolism Obesity (78 abstracts)
Carotidintima-mediacomplexthickness and sex steroid levels in severly obese women of reproductive age
Milina Tančić-Gajić , Miomira Ivović , Ljiljana Marina , Zorana Arizanović , Marija Ilievski , Aleksandra Kendereški , Dragan Micić & Svetlana Vujović
Introduction: Obesity is often accompanied by comorbidites predisposing atherosclerosis. Carotid intima-media complex thickness (CIMT) is consisdered as a marker of initial asymptomatic atherosclerosis. The relationship of sex hormones to obesity and atherosclerosis has been extensively studied.
Objective: The objective of the study was to analyze the correlation CIMT and sex steroid levels in severly obese pre-menopausal women.
Methods and patients: This was a cross-sectional clinical study. The study included 65 severely obese pre-menopausal women aged 35.0±8.7 years with Body Mass Index (BMI) ≥35 kg/m2. Anthropometric parameters and reproductive hormones were measured. Carotid intima-media thickness (CIMT) was assessed using a high-resolution B-mode ultrasound system. The average of maximal values of the right and left CIMT were used as a mean CIMT value.
Results: Anthropometric, hormonal and CIMT data was as follows: TT 124.1±24.0 kg, BMI 47.8±9.2 kg/m2, waist circumference 127.6±17.9 cm, hip circumference 138.5±17.6 cm, FSH 8.1±3.4 IU/l, LH 4.8±2.9 IU/l, estradiol 196.4±109.0 pmol/l, testosterone 2.48±2.9 nmol/l, SHBG 23.1±12.0 nmol/l, androstendione 2.25±1.2 ng/ml, DHEAS 5.2±3.6 μmol/l, CIMT 0.44±0.1 mm. There was significant correlation between CIMT and waist circumference (P<0.05), without significant corelation between CMIT and sex steroid levels (P>0.05).
Conclusion: Obesity, especially central obesity has the crucial influence on carotid intima-media complex thickness and cardiovascular events in the future.
Article tools
My recent searches
My recently viewed abstracts
Authors
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more