ECE2018 Poster Presentations: Diabetes, Obesity and Metabolism Obesity (78 abstracts)
Effectiveness of bariatric surgery in metabolically healthy obese patients
Laura Tuneu 1 , Analia Ramos 1 , Idoia Genua 1 , Nicole Stantonyonge 1 , Francisca Caimari 1 , Carmen Balague 2 , Sonia Fernández-Ananin 2 , Antonio Perez 1 & Inka Miñambres 1
1Endocrinology Department, Hospital de Sant Pau, Barcelona, Spain; 2Surgery Department, Hospital de Sant Pau, Barcelona, Spain.
Objective: To evaluate the effectiveness and security of bariatric surgery in metabolically healthy obese (MHO).
Methods: A retrospective study of a cohort of all obese patients who underwent to bariatric surgery with a minimum two-year follow-up. Databases of all demographic, anthropometric and metabolic characteristics have been collected since 2007. Patients undergoing two surgeries were excluded. We defined as MHO patients those without diagnosis of diabetes or hypoglycemic treatment, basal blood glucose <5.6 mmol/l, HbA1c <5.7% and lipids (Tg <1.7 mmol/l and HDL≥=1 mmol/l men/1.3 mmol/l women) no treated with fibrates. The statistical study was performed using SPSS version 24. Student’s T test, Chi squared test, Pearson’s correlation and multiple lineal regression were used.
Results: A total of 195 patients were included (mean age 48.8±10.6 years, 68.7% of women) In 126 (64.6%) the surgical technique was the Gastric Sleeve whereas in 69 (35.4%) it was by-pass. Prior to surgery, 35 patients (17.9%) were MHO. Patients with MHO had a higher percentage of women compared with patients without MHO (82.9% vs 65.6% P=0.046) and a lower percentage of hypertensive patients (42.9% vs 57.1% P=0.027). In the second and third year post-surgery, MHO patients presented a higher % of excess body weight loss (%EBWL) (80.24% vs 69.52%, P=0.010 and 77.14% vs 63.66%; P=0.015, respectively). Multiple regression analysis showed that age and the presence of MHO inversely correlated with %EBWL. We did not detect any differences of acute complications after bariatric surgery.
Conclusions: Bariatric surgery in patients with MHO is associated with higher weight loss.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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