Endocrine Abstracts

Lipid abnormalities are common in diabetic patients, increasing their cardiovascular risk. The aim of our study is to compare the lipid profile between type 1 and type 2 diabetics. This is a retrospective study of 100 patients, half of them have type 1 diabetes (group 1) and the other half have type 2 diabetes (group 2), hospitalized in department A of the National Institute of Nutrition of Tunis between January 2017 and June 2017. Type 2 diabetics were older than type 1 diabetics. The sex ratio was 0.67 in the first group and 1.17 in the second group. Diabetes evolved from an average of 8.55 years in the 1st group and 11.78 years in the 2nd. It was poorly balanced in both groups with the averages of HbA1c and fasting glucose respectively at 10.72% and 12.54 mmol/l in the 1st group and 10.46% and 10.81 mmol/l in the 2nd group. It was noticed that, for the 2^nd group, the triglycerides levels were statistically higher (1.92 mmol/l vs 1 mmol/l; P value <0.001) and the HDL cholesterol levels were lower (1.09 mmol/l vs 1.27 mmol/l; P value=0.009). We did not find a statistically significant difference in LDL cholesterol levels between the two groups (1.01 g/l in the 1st group and 1.20 g/l in the second group). Our results are in line with the literature. In fact, our type 2 diabetics had a higher triglyceride level and a lower HDL-c level compared with type 1 diabetics. However, the LDL-c level, the most atherogenic fraction of cholesterol, does not seem to be influenced by the type of diabetes.