Endocrine Abstracts

Purpose: To investigate the feasibility and efficacy of US-guided microwave ablation on primary hyperparathyrodism patients who were excluded from surgical treatment.

Materials and methods: From May 2014 to December 2017, 30 parathyroid nodules of 25 patients underwent percutaneous ultrasound-guided MWA in our department. Contrast enhanced ultrasonography, ⁹⁹Tmc-MIBI test, laboratory data and clinical symptoms were evaluated before therapy; 2 hours, 1, 3 days, 1 week and 1, 3, 6 and 12 months after treatment, and every 6-12 months thereafter.

Results: Twenty-two (88%) patients underwent successful ablation among total 25 patients, with 4 patients who underwent ablation of 2 nodules. Minor complications in 3 patients (12%) occurred, including transient fever and voice change.

Conclusions: MWA of hyperplastic parathyroid glands for treating primary HPT proved feasible and effective, while showing meaningful reduction in iPTH, calcium and phosphorus level, minor complications and satisfying clinical outcomes.