ECE2018 Poster Presentations: Calcium and Bone Calcium & Vitamin D metabolism (59 abstracts)
Utility of contrast-enhanced ultrasound in preoperative evaluation of primary hyperparathyroidism
Paola Parra Ramirez , Patricia Martin Rojas Marcos , Antonio Santiago Hernando , Arturo Lisbona Catalan , Alejandro Casto Calvo & Cristina Alvarez Escolá
La Paz University Hospital, Madrid, Spain.
Purpose: The aim of this study was to evaluate the sensitivy of contrast-enhanced ultrasound (CEUS) in the detection of pathological parathyroid gland in patients with primary hyperparathyroidism in comparison to the 99m-MIBI-SPECT scintigraphy.
Methods: 29 patients consecutive (22 female, 7 male) with biochemically confirmed primary hyperparathyroidism, who underwent preoperative imaging with Technetium 99m-MIBI-SPECT scintigraphy and CEUS and subsequent successful parathyroidectomy over a 4 year period were reviewed. All patients were investigated by the same radiologist who was blinded to the result of the scintigraphy.
Results: On pathologic examination, 31 abnormal glands were confirmed. All the glands were adenomatous. CEUS revealed a sensitivity of 62.1% (95% CI 42.3–79.3) for detection of single-gland disease in comparison to 72.4% (95% CI 52.7–87.3) for 99m-MIBI-SPECT scintigraphy. Moreover using CEUS, double adenomas could be detectect in 1 of 2 cases. Alll patients showed normal serum levels of calcium and parathyroid hormone serum levels 3 months after parathyroidectomy.
Conclusion: In our study, CEUS does not replace scintigraphy in localization of pathological parathyroid glands in patients with primary hyperparathyroidism.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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