Endocrine Abstracts

Background: The aim of our study is to show the evaluate relationship between cytological feature of thyroid nodule and TSH level.

Objective: To retrospectively evaluate the usefulness of serum TSH levels as a predictor of thyroid cancer.

Methods: Patients with thyroid nodule(s) who underwent fine-needle aspiration biopsy under ultrasonographic guidance in a Clinica of Administration of the President of the RF were consecutively evaluated.

Results: Eighty patients underwent thyroidectomy and the final diagnoses were malignant in 32(40%) patients, 15 (19%) nodules was follicular adenoma, 33 (41%) was benign nodules. TSH level was significantly higher in patient with thyroid cancer compare with follicular adenoma and other benign nodules\. 30% patients with thyroid cancer had TSH>2.5 μU/ml and only 18% with follicular adenoma, 12% with other benign nodules had TSH level >2.5 μU/ml.

Conclusions: Our study showed that patients with thyroid cancer had significantly higher TSH. TSH level is an independent predictor for thyroid malignancy.