ECE2018 Poster Presentations: Thyroid Thyroid (non-cancer) (105 abstracts)
Arterial stiffness in hyperthyroid patients is deteriorated due to thyroid hormones
Canan Yıldız 1 , Mustafa Altay 2 , Sedat Yıldız 3 , Yavuz Çağır 4 , Tolga Akkan 5 , Yasemin Aydoğan Ünsal 6 & Esin Beyan 6
1Didim State Hospital, Aydın, Turkey; 2Universities of Health Sciences Keçiören Practice and Research Center, Clinic of Endocrinology, Ankara, Turkey; 3Söke Fehime Faik Kocagöz State Hospital, Aydın, Turkey; 4Çubuk Halil Şıvgın State Hospital, Ankara, Turkey; 5Van Çaldıran State Hospital, Van, Turkey; 6Universities of Health Sciences Keçiören Practice and Research Center, Clinic of İnternal Medicine, Ankara, Turkey-.
Aim: It is aimed to evaluate whether arterial stiffness, which is an independent risk indicator for hyperthyroid cardiovascular diseases, is affected by pulse wave analysis (PWA) and to observe changes in patients treated with hyperthyroidism.
Methods: A total of 102 volunteers were included in the study (30 in the overt hyperthyroid group, 28 in the subclinical hyperthyroid group and 14 with euthyroidism by antithyroid therapy and 30 healthy). The arterial stiffness measurements of the subjects participating in the study were performed with the PWA device, which measures the sleeve-based oscillometric measurement of the brachial artery.
Results: Systolic blood pressure, pulse rate, central systolic blood pressure, cardiac output, augmentation index and PWV measurements were significantly higher in the hyperthyroid group than in the control group. The heart rate and PWV in the subclinical hyperthyroid group was significantly higher than the control group. In the euthyroid group, systolic blood pressure, central systolic blood pressure, cardiac output, cardiac index and PWV were found significantly higher than the control group. There was also a negative correlation between Aix@75 and TSH, and a positive correlation between Aix@75 and free thyroid hormones.
Conclusion: In our study, we observed that arterial stiffness was adversely affected by an overt or subclinical increase in thyroid hormones and this correlated with thyroid hormones. We recommend that PWV measurement, which is a simple method for detecting CVD risk, can be used in these patients.
Keywords: Arterial stiffness, augmentation index, hyperthyroidism, pulse wave analysis
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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