ECE2018 Guided Posters Thyroid non cancer - Benign Thyroid disease/ treatment (10 abstracts)
Samara Regional Clinical Oncology Center, Russian Federation, Samara, Russia.
Purpose: Thyroid nodules are an extremely common occurrence. The aim of the study is to evaluate the results of radiofrequency ablation (RFA) for benign symptomatic thyroid nodules.
Materials and methods: Three hundred and sixty two patients with benign symptomatic thyroid nodules (TIRADS/ Bethesda: TIRADS 2, TIRADS 3/THY 2) were included in this research: 355 women and 7 men. The median age of the group was 48 (2476). The mean nodule size was 3.5 (1.59.5) cm. In 280 cases nodules had solid content, in 82 cases mixed solid and cystic content. In case of cystic component, aspiration was needed before performing RFA. The mean duration of RFA was 3 (1.57) min. All the procedures were performed under local anesthesia with real time ultrasound control. Technique of dynamic RFA was applied. Internally cooled 1.01.2 mm-gauge, 70100 mm length, 0.5, 0.7, 1.0, 1.5, 2.0 cm active tip electrodes were used. During the procedure permanent control of hoarse voice was carried out to avoid complications. The follow-up period of patients was 130 months.
Results: At 1-month follow-up the mean volume reduction was 30 (1550)%. In further follow-up the reduction of nodule volume was 50% at 6-month follow-up and 75% at 9-month follow-up. RFA was needed to repeat for 19 patients that had an initial nodule size more than 4.5 cm. None of patients experienced any major complications. A surgery was required for four patients whose nodules did not decrease in volume (15%) during the first month follow-up.
Conclusion: RFA is a minimally invasive technique for treatment of benign thyroid nodules with high clinical efficacy.