Endocrine Abstracts

Research indicates the relationship between beast and thyroid gland. Breast tissue contains the highest concentrations of iodine, so shortfalls in this essential mineral needs have a highly negative impact on breast tissue (R. Thompson, 2015).

Purpose: The study was undertaken to estimate the frequency of the breasts diseases in adolescent girls with endemic goiter.

Patients and methods: The study included 2371 girls (aged 10–18 years). Endemic goiter was diagnosed on the basis of the typical picture of examination and thyroid ultrasound, hormonal analysis. Breast diseases were diagnosed on the basis of clinical signs and typical picture of breast ultrasound. From the girls without thyroid pathology a control group were formed (n=30). Statistical analysis was performed using Mann-Whitney Test. This study has been carried out in accordance with the Helsinki Declaration.

Results: The endemic goiter was diagnosed in 685 (29%) girls. Thyroid function was normal in all girls; however, in comparison group the average TSH levels were 2.8±0.7 and in control group – 1.7±0.5 mIU/l (P=0.033). The investigation shows that in adolescent girls with endemic goiter were diagnosed breast cysts (in 29% cases); fibroadenoma was revealed in 2 patients. All second girls with endemic goiter had cyclic (premenstrual) mastalgia, only 2 girls without thyroid pathology had predmenstrual mastalgia and 1 girls had breast cysts (<0.001). All girls with breast dysplasia and fibroadenoma complained of mastalgia too.

Conclusions: This study has shown a high frequency of the breast diseases among the adolescent girls with endemic goiter. Endemic goiter is risk factor for breast diseases and shows the necessity of for observation and examination of breast.