Endocrine Abstracts

Introduction: Hypoglycemia in diabetic patient is susceptible to infection incidence (abscesses). The aim of our study was to evaluate the clinical, biological, radiological and bacteriological abscesses in diabetic patients.

Patients and methods: We conducted a study prospective, including 74 diabetic patients with a confirmed abscess admitted our hospital, from January to December, 2017. Variables studied were epidemiological, clinical, paraclinical and therapeutic. Analysis was done by excel.

Results: Average age our patients were 51 years, a sex ratio of 1.64 M/F. We found average HbA1c of 8.3% and a kenotic decompensation (60.8%). Localizations were: Brain (1), ORL (9), eye (12), lung (4), mediastinal (1), liver (19), psoas (2), breast (2), conus medullaris (1), genitourinary (6) and skin (15). Clinical presentation was polymorphic and insidious on set but corresponded to the site of the abscess for soft tissue infections. Biological assessment found a high CRP (78.2%) and leukocytosis (60%). Identification was based on bacterial blood cultures (40%) and drained fluid analysis (70%). Germs found were: Klebsiella (42.16%), E.coli (20.3%), pseudomonas aeruginosa (10.8%), staphylococci and/or streptococci (39%), a specificity of Aspergillus fumigates and of Candida tropicalis. Treatment was medical and surgical, antibiotic susceptibility testing with suitable average duration of 2 weeks and a strict glycemic control. Outcome was favorable in 95% of cases.

Conclusion: The poorly controlled diabetes is a field of immunosuppression favoring infection in various locations. Abscess diabetic patients are often localized in the liver and the eye, with a hight prevalence of Klebsella pneumonia.