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Endocrine Abstracts (2018) 56 EP78 | DOI: 10.1530/endoabs.56.EP78

ECE2018 ePoster Presentations Diabetes, Obesity and Metabolism (56 abstracts)

Childhood granuloma annulareas first sign of diabetes mellitus: case series

Anca E Chiriac 1 , Tudor Pinteala 2 , Liliana Foia 3 & Anca Chiriac 4,


1University, Iasi, Romania; 2University of Medicine and Pharmacy ‘Grigore T Popa’, Iasi, Romania; 3University of Medicine ad Pharmacy ‘Grigore T Popa’, Iasi, Romania; 4Nicolina Medical Center, Iasi, Romania; 5Apollonia University, Iasi, Romania.


Ganuloma annulare (GA) is a self-limited inflammatory dermatosis, clinically characterized by the presence of papules arranged in annular or circinate pattern, mostly on the extremities. GA has rarely been reported in childhood, although is a not a rare condition seen in adulthood. Aetiology and pathogenesis of GA are still unknown, although variable associations have been reported, during last decades, with diabetes mellitus, thyroid disorders, HIV infection, malignancies, tuberculosis, Epstein Barr and hepatitis C virus infection or drug administration. Controversial statistically correlation between GA and diabetes mellitus has been published in the literature. We present cases of GA diagnosed in children (based on clinical and histological features) with diabetes mellitus at the moment of diagnosis or diagnosed later and similar cases in children without diabetes mellitus. GA was in a few children a “cutaneous marker” for a newly detected diabetes mellitus. GA patients should be assessed for diabetes mellitus even in children. More studies and reports are needed for establishing the real link between GA and diabetes mellitus.

Volume 56

20th European Congress of Endocrinology

Barcelona, Spain
19 May 2018 - 22 May 2018

European Society of Endocrinology 

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