Endocrine Abstracts

Introduction: Hurthle cell of adenoma (HCA)of thyroid gland is rare neoplasms of the thyroid. They have been found in association with various benign thyroid conditions like Hashimoto’s thyroiditis, hyperthyroidism, nodular goiter, and thyroid neoplasms; where they often represent oncocytic metaplasia. Oncocytic cells are also present in normal parathyroid tissue. Oncocytic parathyroid adenomas, predominantly (more than 70%) or exclusively composed of oncocytic cells are rare (4.4 to 8.4%). We report a patient with an extremely unusual clinical presentation of Hürthle cell adenoma in thyroid and parathyroid adenoma.

Case presentation: We presented a case that of a 50-year-old woman with neck swelling. There were no associated pain or pressure symptoms. Ultrasonography showed a nodule 2 cm diameter in left and showed a nodule 2.5 cm in right thyroid lobewith central and peripheral blood supply. Fine-needle aspiration revealed cellular smears containing monotonous oncocytic cells arranged in monolayered sheets and pseudopapillary structures. No abnormality was detected on the laboratory. Thyroidectomy was done and microscopic examination revealed a HCA of the left thyroidnodule and oncocytic parathyroid adenoma in right thyroid lobe. The patient was discharged on thyroid replacement therapy and has remained healthy after more than 36 months of follow-up.