Endocrine Abstracts

Background and objectives: PCOS is the most common endocrine disorders among women between the ages of 17 and 44. It affects approximately 5% to 10% of this age group. It is one of the leading causes of poor fertility. PCOS patients usually develop thyroid disorders which have an adverse effect on fertility and other hormones. Hence this study was done to estimate levels of LH, FSH, and TSH hormones and to find a correlation between LH,FSH and TSH levels.

Study population: A total of 50 patients of age group 17–44 years were studied for the six months. The patients were included if they satisfied the diagnostic criteria suggested by Androgen Excess PCOS Society. They were excluded if they were having DM II. Hypertension, liver disorders,renal disorders and other chronic diseases. After informed consent and brief clinical history, examination was done to rule out renal disorders, liver disorders or any other condition that would affect the parameters under study. LH.FSH and TSH was estimated. We study a group of patients who are diagnostic with PCOS. In this group we estimate LH, FSH, TSH. Normal levels of FSH is 3–20 mIU/ml, LH<7 mIU/ml, TSH .4–4 uIU/ml.

Interpretation and conclusion: The results of our study showed that levels of LH were high in patients with PCOS with ratio of LH/FST>2:1. Though there is a positive correlation between LH and TSH in both age group it is more significant in older group.TSH levels were high in cases which signifies the evaluation of thyroid function in PCOS patients Thus It was concluded that in PCOS diagnosed patients we should evaluate thyroid functions along with hormonal evaluation to prevent further infertility.