Endocrine Abstracts

Background: Facial feminization or masculinization is particularly important in transpersons, both for self-image and social interaction. Females tend to have a smaller, rounder face, with more prominent cheeks and males tend to have a larger, more square face with frontal bossing. It is unknown whether cross-sex hormones can change these features. However, transgenders themselves often report facial changes due to hormone treatment. Therefore we aim to objectify if hormone tr...

Introduction: Testosterone is known to have an effect on hematocrit levels, with polycythemia as an unwanted side effect. An increase in hematocrit levels is also seen in transmen after starting cross-sex hormonal treatment (CHT) with testosterone. The aim of this study is to investigate the effect of cross-sex hormonal treatment with testosterone on hematocrit levels in the context of the safety aspects of this treatment. The prevalence, determinants and outcome of secondary ...

Introduction: Deficiency of 17-βHSD3 is a rare autosomal recessive disorder of sex development manifesting in XY karyotype individuals. The presentation can range from partial or incomplete virilisation at birth to primary amenorrhoea and virilisation at puberty of an externally phenotypically female individual.Case reports: Case1 A 2-year-old girl presented with ambiguity of external genetalia. She had no significant past medical or surgical histor...