Endocrine Abstracts

Apoptosis is an important process influencing tissues growth, however the assessment of this process in monolayer culture is difficult because apoptotic cells disappear quickly due to secondary necrosis. Most of the methods used with success in vivo is useless in vitro. Our approach to evaluating apoptosis in vitro is based on the possibility to perform multiple assays on the same sample well. The aim of the study was to evaluate the effect of mifepristone (RU-486), a...

Turner Syndrome (TS) is a genetic disorder which affects 0.5–1 in every 2000 females. It is a multi-systemic disease characterised by a deleted or partially missing X chromosome. This deletion results in a higher incidence of primary ovarian failure and removal of the cardio-protective presence of endogenous oestrogen. The aim of this study was to analyse the prevalence of cardiovascular risk factors in a TS cohort and to assess the steps taken to modify these risk factor...