Endocrine Abstracts

Intracranial germ cell tumors (GCTs) account for only 0.4–3.4% of all central nervous system (CNS) tumors. A 18 year old patient with an unremarkable medical history was presented to the ophtalmology outpatient clinic with a 2 month history of loss of vision at left eye and blurrred vision at right also headache and fatigue. Ophtalmological examination showed loss of visual acuity at left eye and decreased 0.05–0.1 at the right and bilateral optic atrophy. Further physical examination showed sexual infantilism (poor beard, pubic and axillary hair growth, small testis). The patient’s skin was dry and pale. Endocrinological examination showed panhypopituitarsm. Pituitary MR imaging demonstrated contrast enhancing mass lesion at suprasellar cisternal region which outstrecthed to posterior perimesencephalic cisternal region. The mass resected by craniotomy and pathology showed germinoma.Chemotherapy and radiation therapy were administered. He is still using prednisolon, L-thyroxine and human chorionic gonadotropin treatment.