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Endocrine Abstracts

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20th European Congress of Endocrinology

Barcelona, Spain
19 May 2018 - 22 May 2018

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ECE 2018, 19 - 22 May 2018; Barcelona, Spain

Poster Presentations: Interdisciplinary Endocrinology

Developmental endocrinology

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Clinical case reports - Thyroid/Others
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Diabetes (to include epidemiology, pathophysiology)

ea0056p637 | Developmental endocrinology | ECE2018

Effect of desacyl ghrelin on protein expression of GHS-R1 receptor in human placental cells

de la Luz Jaramillo-Narvaez Maria , Guadalupe Leon-Verdin Ma. , Martinez Montes Federico , Luisa Lazo de la Vega Monroy Maria , Barbosa Sabanero Gloria

Introduction: Ghrelin is an orexigenic hormone with two isoforms: Acyl Ghrelin (AG) and Desacyl Ghrelin (DAG). AG binds to its specific receptor GHS-R1 and stimulates growth hormone secretion. DAG also binds to GHS-R1 receptor, but with 1000 times less affinity than AG. Effect of DAG on cell proliferation and inhibition of apoptosis has been reported. However, there are no studies of DAG function in human placenta. For first time, this work analyzed the effect of DAG on viabil...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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