Endocrine Abstracts

Introduction and objectives: The most important risk factors of chronic kidney disease (CKD) are diabetes and hypertension. In addition, obesity and metabolic syndrome (MetS) are independent predictive factors of CKD. The objective of our study was to investigate if MetS affects renal function of patients who underwent partial nephrectomy for localized renal cell carcinoma (RCC).Patients and methods: 50 cases of T1N0M0 RCC patients who underwent partial ...

Androgenic alopecia (AGA) is an important clinical issue that can cause significant cosmetic problems. Many factors such as genetic, androgen hormones, environmental factors, and inflammation are involved in the pathogenesis of androgenic alopecia. Insulin and insulin resistance have been found increased in individuals with AGA. There are many proinflammatory substances which are playing role in the pathogenesis of androgenic alopecia. Secreted frizzled related protein-4 (SFRP...

Background: In heart failure with reduced ejection fraction (HFrEF), catabolic mechanisms have a strong negative impact on morbidity and mortality. The relationship between anabolic hormonal deficit, thyroid function and heart failure with preserved ejection fraction (HFpEF) has still been poorly investigated. For this reason, we tried to define the prevalence of multi-hormonal deficiencies in HFpEF patients and the relationships between hormonal deficits and echocardiographic...

Introduction and objectives: Transsexuality refers to discrepancy between the assigned sex/gender at birth and the one that the subject identifies with. The use of the cross hormone treatment as sex/gender change method implies the necessity of monitorize the hormone levels and potential treatment risks. Our study tries to evaluate the relationship between the hormone changes and the changes in the cardiovascular risk factors and the bone mineral density.<p class="abstext"...

Introduction: Two major strategies can be used to verify the diagnosis of ascending aortic dilatation in Turner syndrome (TS): the diameter of the aorta adjusted for body surface area (BSA) can be estimated or the ratio of the ascending/descending aorta may be assessed.Aim: To identify the difference of the prevalence of ascending aortic dilatation in patients with Turner syndrome by measuring the diameter of the ascending aorta adjusted for BSA and by e...

Introduction: Fibroblast growth factor-21 (FGF-21) is a recently discovered hormone acting as a central regulator of metabolism via adaptation of glucose homeostasis, insulin sensitivity, and ketogenesis. While acute systemic inflammatory conditions come along with profound alterations of metabolism, the role of FGF-21 in these acute phase responses is still unknown.Methods: This is a secondary analysis of two randomized, controlled trials in patients pr...