Endocrine Abstracts

Background and aim: The TaqI (rs1800497) polymorphism of the Dopamine Receptor type 2 (DRD2) gene allele has been commonly related to increased ad lib food intake, weight gain, and risk for obesity overeating and risk for obesity. We supposed to find associations between body mass index (BMI), the TaqI (rs1800497) polymorphism of the Dopamine Receptor type 2 (DRD2) gene and plasma leptin and dopamine in children with alimentary and extreme obesity and normal weight.<p clas...

Background and aims: The prevalence of metabolic syndrome in Korean youth population has been increased by introduction of Western diet in the past decades. The aim of this study was to investigate the incidence of urinary ketosis and correlation with metabolic indices in healthy adolescents in Korea.Materials and methods: This was a large-scale, community-based study conducted from January 2007 to December 2010. A total of 1,349 subjects (749 males and ...

Thrombocytes play important role in pathogenesis of diabetic vascular complications.Aim: To study peculiarities of functional activity of thrombocytes in adolescents with diabetes mellitus type 1 (T1DM).Patients and methods: 98 adolescents (42 boys, 56 girls) 12–16 y.o. with T1DM were examined. The duration of the disease was: less than 1 year in 25 patients (HbAc1 7.4±0.3%) – group 1, from 1 to 5 years in 40 patient...