ECE2018 Poster Presentations: Diabetes, Obesity and Metabolism Diabetes therapy (43 abstracts)
Perinatal outcomes in Mexican women with mild gestational diabetes mellitus without treatment diagnosed by the international association of diabetes and pregnancy study groups criteria
Nayeli Martinez Cruz , Enrique Reyes Muñoz , Karla P. Soriano Ortega , Lidia Arce Sanchez , Carlos Ortega Gonzalez , Ursula Torres Herrera , Salvador Espino y Sosa & Aracely Montoya Estrada
Instituto Nacional de Perinatología, Ciudad de Mexico, Mexico.
Aims: To compare the risk of adverse perinatal outcomes (APO) between pregnant women with mild gestational diabetes mellitus (GDM) by International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria without treatment versus women without GDM.
Methods: A retrospective cohort study. We included pregnant women with prenatal care and delivery at our Institution. Group 1, women with mild GDM defined by one abnormal glucose value according to IADPSG criteria; fasting: 5.1–5.2 mmol/l (92–94 mg/dl) or 2 h 8.5–8.56 mmol/l (153–154 mg/dl), which did not receive treatment for GDM. Group 2, women without GDM matched by maternal age and pre-gestational body mass index (BMI). We excluded women with pregestacional diabetes, any chronic disease, and multiple pregnancies.
Results: 282 women were included in each group. There were not significant differences in basal characteristics between groups. The newborn weight was significantly higher in group 1 (3042.4±499 g) vs group 2 (2910±565 g) P=0.003, however the incidence of neonates large for gestational age (LGA) and macrosomic were similar in both groups 6 vs 5.7% and 2.1 vs 2.2% respectively. There were no differences in the risk of APO such as; preeclampsia, gestational hypertension, cesarean, preterm delivery and premature rupture of membranes. In a sub-analysis we showed that LGA was significantly higher in women with pre-gestational BMI ≥30 kg/m2 in both groups.
Conclusions: The risk of APO is similar in Mexican women with mild GDM diagnosed by IADPSG criteria without treatment compared to pregnant women without GDM. The pre-gestational BMI is an independent risk factor for neonates LGA.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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