ECE2018 Poster Presentations: Diabetes, Obesity and Metabolism Cardiovascular Endocrinology and Lipid Metabolism (25 abstracts)
Improved lipid profile and cardiovascular risk factors after bariatric surgery
Elena González , Ana Urioste , David Barajas , Paula Fernández , Tania Ramos , Mirian Alejo , Ana Hernández , Sara García , Begoña Pintor , Luis González , Isidoro Cano & María Ballesteros
Complejo Hospitalario León, León, Spain.
Background: Bariatric Surgery (BS) is an effective treatment for the metabolic control of obese patients. One of its purposes is to improve the lipid profile and reduce cardiovascular risk.
Aims: • To determine the changes in lipid profile and other cardiovascular risk factors before and one year after BS.
• To assess differences in lipid parameters depending on the surgical procedure used.
• To assess pre and post BS admissions in the cardiology ward.
Methods: Retrospective observational study of 418 patients who underwent BS from 1998 to 2017. Registered variables were gender, age, BMI, type of surgery, total cholesterol, HDL, triglycerides, blood pressure, blood glucose and HbA1c, baseline and one year after surgery (expressed as median and interquartile range) and compared according to the surgical procedure. The number and reasons for admission in cardiology before and after BS for patients in our health area was also recorded.
Results: Of the 418 patients, 76.3% were women. 88% underwent malabsorptive-restrictive procedures and 12% underwent pure restrictive procedures. Median age and BMI were 44.98 (16.33) years and 46.94 (8.97) kg. Levels of cholesterol, HDL, triglycerides, systolic blood pressure, diastolic blood pressure, blood glucose and HbA1c were 192 (148.5) mg/dl, 45 (15.75) mg/dl, 119 (80.75) mg/dl, 140 (18.75) mmHg, 90 (14.75) mmHg, 98.5 (29, 75) mg/dl, 5.8 (1.08)% respectively, and were reduced significantly one year after BS (P<0.001) to: 142.5 (46.75) mg/dl, 48.5 (16,75) mg/dl, 97 (61) mg/dl, 90 (14.75) mmHg, 75.5 (18.75) mmHg, 82.5 (12) mg/dl, 5.05 (0.5)%. Improvement in cholesterol, diastolic blood pressure and Glu/HbA1c was higher for malabsorptive procedures (P<0.05). Among patients in the area of León, 2% had an admission in the cardiology ward before BS (50% were ischemic). 4% were admitted after BS: 8.3% due to ischemic causes and 66.6% because of arrhythmias.
Conclusions: Bariatric surgery significantly improves lipid parameters and cardiovascular risk factors in one year, especially with malabsorptive procedures. The rate of admission for ischemic heart disease is lower than the reported to general population in our community (5.7/10000 population vs 8.25/10000 inhabitants in 2014 in the community of Castilla y León).
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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