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Endocrine Abstracts (2018) 56 P289 | DOI: 10.1530/endoabs.56.P289

1Department of Geriatric Medicine, Ege University Medical Faculty, Izmir, Turkey; 2Ataturk Training and Research Hospital, Department of Endocrinology and metabolism, Izmir, Turkey.


Objective: In recent years, many studies have been conducted on the beneficial effects of vitamin D. Vitamin D have many important effects on calcium metabolism, skeletal system and also on different systems. Low serum vitamin D levels are predictors of type 2 diabetes mellitus, cancer, cardiovascular diseases, immunological diseases and even mortality. The relationships between vitamin D and cardiovascular diseases can be explained by the lipid-lowering effect of vitamin D. In many studies, there is general agreement that high serum vitamin D levels are associated with a healthy serum lipid profile. The aim of this study was to investigate whether vitamin D levels are associated with lipid levels in outpatients, and to compare the patients above and below 60 years of age.

Material and methods: The medical records of patients who applied to outpatient clinic between January 2015 and August 2017 were reviewed. 236 outpatients aged 19–88 years who had serum 25-hydroxyvitamin D (25(OH)D) levels, total cholesterol, LDL-cholesterol, high density lipoprotein (HDL) cholesterol and triglyceride levels were included in the study. Patients’ body mass index (BMI) was calculated. Overweight was defined as BMI (kg/m2) between 25.0 and 29.9 and obesity was defined as BMI ≥30.0. Total cholesterol levels ≥200 mg/dl, LDL cholesterol levels ≥140 mg/dl and triglyceride levels ≥ 150 mg/dl were classified as high. HDL-cholesterol levels <40 mg/dl were defined as low. Serum 25(OH)D level <50 nmol/l, or <20 ng/ml, is an indication of vitamin D deficiency.

Results: This study was conducted with 236 outpatients aged 19–88 years. 46.2% of the study population were over 60 years old, 83.5% were female, 18.2% were normal weight, 50.4% were overweight and 31.4% were obese. 56.8% of the outpatients had high total cholesterol levels, 38.1% of had high LDL cholesterol levels and 30.1% of had high triglyceride levels. 14% of the outpatients had low HDL cholesterol levels. The prevalance of vitamin D deficiency was 49.6% (95% CI, 41–58%).

Conclusion: Patients with increased 25(OH)D levels in epidemiological studies; there was a significant decrease in total cholesterol, LDL cholesterol and triglyceride levels and an increase in HDL cholesterol levels (1–3). But, in our study, there was no statistically significant relationship between vitamin D deficiency and lipid profile in patients over 60 years and under 60 years of age. We planned to increase the number of patients.

Volume 56

20th European Congress of Endocrinology

Barcelona, Spain
19 May 2018 - 22 May 2018

European Society of Endocrinology 

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