Endocrine Abstracts

Background: Osteoporosis is a not uncommon complication of endocrine disease. It may even be accompanied by endocrinopathy. The aim of study was to determine mineral bone density profile of patients with endocrinopathy and define the osteoporosis and osteopenia prevalence in these patients.

Materials and methods: Descriptive study included 177 patients followed for endocrinopathy (hypercorticism, hyperparathyroidism, prolactinoma and hypogonadism) in Endocrinology and Diabetology department of Ibn Rochd University Hospital of Casablanca, from 2011 to 2017. Each patient had a phosphocalcic balance, a vitamin D test and bone densitometry. Several variables were studied such as age, gender, fracture antecedant. Statistical analysis performed by the software SPSS.16.

Results: Mean age of our patients was 38 (16-73) years, with a female predominance (sex ratio: 0.3). The etiologies were represented by hyperparathyroidismin 65 patients, hypercorticismin 61 patients, prolactinoma in 12 patients and hypogonadism in 39 patients. An abnormal bone density was found in 85% of patients. Osteoporosis prevalence was 68% with predominance of the spine localization during hypercoticism (45%) and hypogonadism (38%) with an average T-score of -1.98±1 among patients with hyperparathyroidism. Osteoporosis predominated in the forearm in 35% of patients. Osteopenia was found in 37% of patients with femoral predominance. Vitamin D deficiency was found in 74% of our patients. These bone density abnormalities were revealed by endocrine pathology in 75% of patients, 18% of whom were at the stage of complications such as bone fractures.

Conclusion: This work shows a high incidence of osteoporosis and osteopenia in patients treated for endocrine diseases especially who followed for hypercorticism and hypogonadism and drove us to place the interests of systematically seek an abnormal bone density before any endocrine disorder which can cause rheumatic disorder.