Endocrine Abstracts

The gonadotropin-releasing hormone (GnRH) neurons are key cells regulating fertility in all mammals including humans. They release GnRH in an episodic manner to drive the pulsatile secretion of luteinizing hormone (LH) and follicle-stimulating hormone critical for gonadal function. Remarkably, the GnRH neurons are not born in the brain but arise from the nose and migrate into the brain during early embryogenesis. This unique origin engenders a variety of unusual and unique pro...