Endocrine Abstracts

Association of type 2 diabetes, NAFLD, intestinal dysbiosis and endotoxemia is a trigger factor of cytokine cascade which manifest in proinflammatory state development, insulin resistance, hyperglycemia and dyslipidemia progression. The aim of this study is to reveal the effect of multiprobiotic Symbiter (symbiotic association of 14–24 strains of Bifidobacterium Lactobacillus, Propionibacterium, Lactococcus lactis, Streptococcus, Acetobacter aceti) and hepatoprotector Glu...

The advent of Web-based patient management technologies, including Web-based messaging, video conferencing, remote monitoring of vital signs, and Web-based educational programs, has resulted in the recognition that telemedicine may benefit diabetic patients with limited access to healthcare providers and/or a high burden of disease. In this regard, 24-week prospective multi-center randomized controlled trial involved 338 adult patients with type 2 diabetes at four university h...

Background: There aren’t published randomized studies comparing the clinical impact of degludec and Glragina U300 in the treatment of type 1 diabetes patients. (T1DP)Objective: To compare efficacy and safety of the new long acting analogues Glargine U 300 and Degludec in 300 Type1 diabetes patients treated with basal/bolus treatment.(BBT)Material and methods: Randomized control study 1.1 in 300 T1DP treated with BBT with glarg...

Background: Real life implementation studies performed in different settings/populations proved that lifestyle interventions in prevention of DM2 can be effective. However, little is known about long term results of these translational studies and determinants of the outcomes.Aim: The purpose of this study was to examine the maintenance of diabetes type 2 risk factor during 3 year follow-up and to examine determinants of long term outcomes.<p class="...

Introduction: Many type 2 diabetes patients continue to have poor glycaemic control and would benefit from insulin therapy. One of the risks that hinders insulin use is hypoglycemia. Optimal insulin therapy should therefore minimize the risk of hypoglycemia while improving glycemic control. Newer insulin preparations degludec and glargin 300 units/ml show more even and prolonged pharmacokinetic profile, enabling an evenly distributed daytime glucose-lowering effect with high r...

Introduction: Adult-onset autoimmune diabetes (AID) has two different phenotypes: classic type 1 diabetes mellitus (T1DM), with insulin requirement just after diagnosis, and latent autoimmune diabetes in adults (LADA). According to the Immunology of Diabetes Society, LADA diagnostic criteria are: age of onset of 30 years or more, any islet autoantibody, absence of insulin requirement for at least 6 months. The purpose of this study is to characterize patients with AID followed...

Purpose: Steroid usage may cause hyperglycaemia in non-diabetic patients. We aimed to detect the onset of hyperglycaemia and the best time for glucose measuring over a short time span (1–5 days) in non-diabetic patients who commenced moderate or high dose steroid therapy.Methods: Electronic data of patients, who were commenced moderate or high dose steroid therapy (15–60 mg prednisolone or equivalent dose methyl prednisolone) due to inflammator...

We planned to research the effect of the regular exercise of type 2 diabetes mellitus (DM) patients on metabolic control, malondialdehyde (MDA) as the oxidative stress marker and on the quality of life. The study has been carried out 64 patients diagnosed with Type 2 DM for at least 6 months, without any microvascular/macrovascular complication for diabetes, using oral anti-diabetic agent with a HbA1c value of less than 9%. The 31 patients were asked to carry out aerobic exerc...

Background: Medical nutrition therapy is an important part of the management of type 1 diabetes mellitus (T1DM). Proper adherence to a healthy diet may have a favorable impact on diabetic complications. Our aim was to assess differences in food and nutrient intake of type 1 diabetic patients with and without diabetic retinopathy (DR).Subjects and methods: This was a two-center, cross-sectional study in patients diagnosed with T1DM with and without DR. Su...

Background: Gastric Bypass surgery (Bypass) is recognized as the ultimate metabolic surgery. The success in type 2 Diabetes (DM2) remission documented in patients submitted to Vertical Sleeve Gastrectomy (Sleeve) made questionable the hypothesis that this restrictive surgery has beneficial metabolic effects.Main goal: Comparing the Bypass and Sleeve’s efficacy in DM2 remission.Methods: Retrospective study of 112 diabetic patie...

Introduction: Post-stroke hyperglycemia affects two-thirds of the patients during acute ischaemic stroke and it is associated with poorer outcomes. The aim of this study was to analyze the differences between the diabetic and non- diabetic patients that underwent an acute stroke.Methods: Retrospective descriptive study of patients admitted to the Acute Stroke Unit from January to June 2017, including blood parameters, glycemic treatment and 3 months outc...

Objectives: The aim of this study is to compare Friedewaldestimated and directly measured lowdensity lipoprotein cholesterol (LDLC) values and assess the concordance in guideline risk classification between the two methods.Methods: The data were derived from the 2009 to 2011 Korea National Health and Nutrition Survey (KNHANES). Analysis was done for 6454 subjects with lipid panels – total cholesterol (TC), directly measured LDL-C, high-density lipop...