ECE2018 Guided Posters Diabetes Complications (11 abstracts)
The BMI and skeletal muscle mass as a risk factor of carotid atherosclerosis in patients with type 2 diabetes
Se-Hwa Kim 1 , Soo-Kyung Kim 2 , Young-Ju Choi 3 , Seok-Won Park 2 , Eun-Jig Lee 4 , Yong-Wook Cho 2 & Kap-Bum Huh 3
Background: The body mass index (BMI) is the most widely used method of assessing fat accumulation, and is recognized as an independent risk factor for cardiometabolic diseases. However, there might be substantial variations in the fat or muscle amount among persons with a similar BMI. The aim of the present study was to investigate whether BMI and skeletal muscle mass (SMM) estimated from by bioelectrical impedance analysis (BIA) are associated with carotid atherosclerosis in patient with type 2 diabetes.
Methods: This was an observational study performed in 4437 patients with type 2 diabetes. Anthropometric measures and BIA were performed for each subject. Carotid atherosclerosis was defined by having a clearly isolated focal plaque or mean carotid intima-media thickness (CIMT) ≥ 1.1 mm.
Results: CIMT and the frequency of carotid atherosclerosis were higher with decreasing SMM quartiles rather than with increasing BMI quartiles in both genders. The SMM to BMI ratio was significantly related with CIMT and carotid atherosclerosis in both genders, even after adjusting for potential confounders (adjusted odds ratio of carotid atherosclerosis for the highest quartile of this ratio compared with the lowest quartile being 0.630 [95% CI, 0.440–0.901] and 0.582 [0.391–0.860] in men and women, respectively).
Conclusions: BMI alone could not assess the carotid atherosclerotic risk. An additionally estimation for skeletal muscle may provide a role in assessing atherosclerotic burden in patients with type 2 diabetes.
Article tools
My recent searches
My recently viewed abstracts
Authors
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more