ECE2018 ePoster Presentations Pituitary and Neuroendocrinology (36 abstracts)
Laribosiere Hospital, Paris, France.
We herein describe a 55-year-old woman who showed a dramatic improvement in glucose control following treatment for co-existing acromegaly and Cushings syndrome. The co-occurrence of acromegaly and Cushings syndrome in one individual is extremely rare. This patient was diagnosed as having diabetes mellitus 7 years ago. Afterwards, in spite of insulin therapy, her hyperglycemia could not be well controlled. Endocrinological and radiological examinations revealed subclinical adrenal Cushings syndrome. Successful treatment for these endocrinopathies resulted in greatly improved blood sugar control because of a reduction in insulin resistance. The insulin treatment was discontinued following the treatment of acromegaly. This report describes insulin resistance before and after treatment in a case of acromegaly accompanied by adrenal preclinical Cushings syndrome.