ECE2018 ePoster Presentations Diabetes, Obesity and Metabolism (56 abstracts)
Diabetic foot ulcers (DFU) in eastern India: an observational
Edward Jude 1, , Ghanshyam Goyal 3 , Rashmi Sahay 4 , Resmi Gupta 4 , S Banka 3 , Rekha Srivastava 3 , Shammi Kapoor 3 & Jaydeep Mazumder 3
1University of Manchester, Manchester, UK; 2Tameside Hospital NHS Foundation Trust, Ashton under Lyne, UK; 3ILS Hospital, Kolkata, India; 4Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA.
Foot ulceration in diabetes is known to represent a major cause of morbidity and mortality, and carry considerable financial implications for healthcare organisations. Little research has studied the outcomes for patients with foot ulcer in Eastern India. We identified 717 patients aged 18 years and over with Type 2 diabetes mellitus (T2DM) who presented for management of their diabetic foot ulcers from February 2013-February 2016 with mean follow up of 2 years. Methods: Of the 717 patients (574 male (71.4%), mean age 56 (range 49–63) years); 645 (89.9%) healed during follow up. We compared risk factors between healed and non-healed ulcers. All patients received standard of care including off loading where appropriate.
Results: There was no difference in age, gender, duration of diabetes and HbA1c and site or number of ulcers on the feet or amputation between healed and non-healed groups; but patients were heavier in the latter group. There was however increased vascular calcification in the non healed group and also higher Wagner grade but more use of total contact casting (TCC). In a multivariable logistic regression analysis the odds ratios for non-healing were: weight (1.02), duration of ulcer (1.27), higher Wagner classification (1.52), vascular calcification (yes/no) (2.21) and use of TCC (2.24).
Conclusion: Calcification of foot arteries, higher grade ulcers, longer duration of ulcer and patient’s weight play a role in non-healing. Having a better understanding about the risk factors involved in the non-healing of DFU and treatment strategies provided will help in reducing the prevalence of foot ulcers. Further studies are required to see if these modifiable risk factors need to be looked at to improve wound healing.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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