Endocrine Abstracts

Primary subclinical hypothyroidism (SH) is commonly defined by laboratory parameters (TSH above the commonly accepted reference range of about 0.4–4.0 mU/l with normal FT4). This definition does not implies actual thyroid dysfunction, since individual variations of hypothalamic-pituitary feedback set point due to endogenous (genetic, age/gender, NTIS) or exogenous (e.g. drugs) factors may lead to TSH increase in the absence of thyroid disease. Thus, to answer the question...

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