Endocrine Abstracts

In women, the anti-Mullerian hormone (AMH) is secreted by the granulosa cells of the growing follicles. Its assay is therefore strongly correlated with the antral follicular count and represents a reliable marker of the ovarian reserve. It also has the advantage of being very reproducible since it has little intra- and inter-cyclic variation. However, it seems to be a good quantitative reflection of the ovarian reserve but not qualitative. This drawback does not make this assa...

AMH is a dimeric protein hormone and a member of the TGF-β superfamily. AMH is first expressed in granulosa cells of primary follicles and expression persists in growing follicles up to 6 mm in diameter. In follicle stages beyond 8 mm, AMH expression diminishes and ultimately becomes undetectable once the follicle becomes FSH-dependent1. Its measurement is strongly correlated with antral follicle count and represents a reliable marker of ovarian function. It is reproducib...