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Endocrine Abstracts (2017) 49 EP563 | DOI: 10.1530/endoabs.49.EP563

Hospital de Valme, Sevilla, Spain.


Introduction and objectives: Having frequent hypoglycaemias can enable the appareance of severe and unnoticed hypoglycaemias, as well as favouring vascular damage in these patients. Our objective is to evaluate de incidende of severe hypoglycaemias (SH) in patients with Diabetes Mellitus type 1 and the reduction of perceived hypoglycaemias.

Material and methods: A prospective study was conducted. Patients attending to their Endocrinology appointments between September 2013 and January 2014 were surveyed to evaluate their capacity to perceive hypoglycaemias (Clark’s test). Patients with a test result compatible with a diminished capacity to sense hypoglycaemia were tracked 2 years later. The data was analysed using a Chi-squared test (IC 95%) with SPSS 21.0.

Results: 104 patients were surveyed, out of which 41 had a diminished capacity to perceive hypoglycaemia (mean age 36.6±11.6 years, 61% women, HbA1c, 26%±1.04% and 58.5% had >20 years diabetes evolution). After 2 years, 43.9% referred having had severe hypoglycaemias, out of those 55.6% had had more than 3 episodes and 33.3% had had a loss of consciousness. 19.5% had an insulin pump (21.4% in patients with severe hypoglycaemia). We found a statistically significance between Clark’s test results and severe hypoglycaemias (P<0.002).

Conclusions: A pathological Clark’s test may be able to identify patients at risk for severe hypoglycaemia, which makes it a useful tool to detect this group of patients. If a high incidence of severe hypoglycaemia is observed, measured should be taken to educate this patients to be able to recognize and interpret the symptoms of low blood glucose as well as developing therapeutic strategies to avoid them, all of which would improve their quality of life.

Volume 49

19th European Congress of Endocrinology

Lisbon, Portugal
20 May 2017 - 23 May 2017

European Society of Endocrinology 

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