Endocrine Abstracts

Introduction: Distant metastasis caused by thyroid carcinoma is common and usually found in lung or bone. Clinically detectebale, welldifferenciated metastatic thyroid carcinoma to the kidney is rare. Only 16 cases have been reported in the littérature. We describe a case of metastatic vesicular thyroid carcinoma to the bilateral kidneys in a 61 years women, with bone, pulmonary lever and lynph nodes metastasis.

Case report: A 61 old women with a past history of thyroid tumor that had been surgically treated 19 years earlier She underwent a total thyroidectomy, radiotherapy, s ablation treatment with iodine 131 and thyroxin suppression therapy (200 μg/day) and has been diagnosed as vesicular thyroid cancer developped a left renal metastasis with chest pain. The lesion was detected with iodine 131 scintigraphy which measured in the CT Scan 68/60/13 mm. Biological tests showed: The thyroglobulin 3000 ng/ml (0.8–55) - TSH=0.02 μUI/ml. Subsequent surgery and histopathology analysis of the renal lesion confirmed the diagnosis of vesicular thyroid metastatic carcinoma. Four years later a second metastasis of the right kidney appeared with pulmonary, bone, leaver and lymph nods metastasis. She underwent surgery where metastatic carcinoma was confirmed (3 cm of diameter).

Discussion - Conclusion: Only few cases of metastatic spread to the kidneys are described in the literature. 16 cases have been reported. They are mostly unique and rarely bilateral. The common use of the ultrasound and the CT Scan in assessment of monitoring of a cancer, patient allowed bringing to light more frequently this kind of lesion. The concomitant existence of metastasis in the other sites is variously appreciated in the literature. They varies from 50 to 100% observed cases and pejorative from the point of view of the prognosis. The most frequent locations are pulmonary, mediastinal and bone. The patient has benefited a dialysis treatment and deceased a year later.