ECE2017 Eposter Presentations: Thyroid Thyroid (non-cancer) (260 abstracts)
Complementary thyroidectomy in papillary thyroid cancer
Yusuf Durmus 1 , Mehmet Celik 2 , Buket Yilmaz Bulbul 2 , Semra Ayturk 2 , Ebru Tastekin 3 , Nuray Can 3 , Atakan Sezer 4 , Funda Ustun 5 & Sibel Guldiken 2
1Trakya University, Medical Faculty, Department of Internal Medicine, Edirne, Turkey; 2Trakya University, Medical Faculty, Department of Endocrinology and Metabolism, Edirne, Turkey; 3Trakya University, Medical Faculty, Department of Pathology, Edirne, Turkey; 4Trakya University, Medical Faculty, Department of Surgery, Edirne, Turkey; 5Trakya University, Medical Faculty, Department of Nuclear Medicine, Edirne, Turkey.
Aim: ATA guideline recommends complementary thyroidectomy after thyroid lobectomy in case of tumor diameter>1 cm, in the presence of metastatic tumor, invasion, history of radiation therapy, familial history of thyroid cancer, multifocal or agressive variant tumor. In this study, we aimed to evaluate the relationship between the necessity of complementary thyroidectomy and post-surgery clinical, radiologic and histopathologic results in the patients who underwent complementary thyroidectomy for papillary thyroid cancer (PTC).
Method: We retrospectively evaluated the data of 110 patients who had undergone complementary thyroidectomy following lobectomy and been followed-up by our department between January 2010 and January 2017. 67 of these patients had unifocal and 43 had multifocal PTC. The relationship between demographic data, histopathologic results, BRAF mutation status and complementary thyroidectomy was evaluated.
Results: Among 110 patients, 85 (77.2%) were female and 25 (22.8%) were male. The mean age of the subjects was 47.8±12.3 years. Following complementary surgery, 70 (63.6%) of the patients were found to have benign pathology and 40 (36.4%) were found to have PTC on controlateral lobe. Parameters such as gender, age, hormonal status, presence of Hashimoto disease, tumoral variant, lymphocytic thyroiditis, tumor localisation, tumoral focality, number of tumoral foci, perineural invasion, capsular invasion, lymphovascular invasion, extrathyroidal extension, lymph node metastasis and BRAFV600E mutation status were found to be insignificant for complementray thyroidectomy.
Conclusion: We suggest that unifocality or multifocality of single lobe tumor is not determinative for complementary surgery during initial operation. However, long-term follow-up data is required to determine the effect complementary thyroidectomy on prognosis and mortality.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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