ECE2017 Eposter Presentations: Thyroid Thyroid (non-cancer) (260 abstracts)
Is there an impact of the concurrent presence of chronic autoimmune thyroiditis in differentiated thyroid cancer patients?
Sorina Martin 1, , Oana Budianu 3 , Oana Ion 3 , Andreea Grigore 3 , Anca Sirbu 1, , Carmen Barbu 1, , Cosmin Giulea 4, , Adrian Miron 4, , Florin Andrei 6 & Simona Fica 1,
1Endocrinology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania; 2Endocrinology Department, Elias Hospital, Bucharest, Romania; 3Carol Davila University of Medicine and Pharmacy, Bucharest, Romania; 4Surgery Department, Elias Hospital, Bucharest, Romania; 5Surgery Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania; 6Pathology Department, Elias Hospital, Bucharest, Romania.
Background: The association between differentiated thyroid carcinoma (DTC) and autoimmune thyroiditis (AT) has been reported in numerous studies, yet the impact of the concurrent presence of AT and DTC remains controversial.
Methods: We retrospectively analysed the files of 493 patients submitted to thyroidectomy in our surgery department between January 2012 and September 2015.
Results: A total of 86 patients with DTC were enrolled, mean age 53.99±13.91 years, 83.7% females. 25 (29%) patients, all women, associated biochemical and/or histopathological AT. We found no significant differences between patients with DTC and AT compared to patients without AT regarding the ultrasound characteristics of the thyroid nodules: nodule diameter (P=0.330), echogenicity (P=0.572), halo presence (P=0.528), microcalcifications (P=0.347), vascularization (P=0.199) and lymph nodes involvement (P=0.418), nor the histopathological characteristics of the DTC: tumor subtype (P=0.100), tumor diameter (P=0.726), the presence of multifocality (P=0.829), TNM staging (P=0.672), vascular invasion (P=0.149), capsular invasion (P=0.617), extracapsular extension (P=0.713) or the presence of local lymph nodes metastasis (P=0.888).
Conclusions: Although our data showed a high prevalence of AT in patients with DTC, we found no significant differences regarding the ultrasound and histopathological characteristics of DTC in patients that concurrently had AT compared to patients without AT.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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