ECE2017 Eposter Presentations: Thyroid Clinical case reports - Thyroid/Others (30 abstracts)
Synchronous papillary thyroid carcinoma and primary hyperparathyroidism: a rare association
Nadia Khessairi , Ibtissem Oueslati , Malika Chihaoui , Meriem Yazidi , Ons Rjeb , Fatma Chaker & Hedia Slimane
Department of Endocrinology, La Rabta hospital, Tunis, Tunisia.
Introduction: Although the association between parathyroid and thyroid diseases is not uncommon, the coexisting of parathyroid adenoma causing primary hyperparathyroidism (PHPT) and papillary thyroid carcinoma (PTC) is rare. Probably this can be partially explained by different embryologic origin of thyroid and parathyroid cells. Herein, we report a case of PHPT associated with synchronous bifocal PTC.
Observation: A 65-year-old woman was referred to our department with incidental hypercalcaemia and biochemical PHPT. A Technetium (99mTc) sestamibi scintigraphy showed a distinct functioning nodule in the lower right pole of the thyroid. Ultrasonography of the neck revealed parathyroid adenoma at the inferior pole of the right thyroid lobe and bilateral thyroid nodules. The patient was subjected to uncomplicated right inferior parathyroidectomy and synchronous total thyroidectomy. Postoperative histopathological examination confirmed the diagnosis of parathyroid adenoma with coincidence of papillary thyroid carcinoma. After surgery, serum parathormone and calcium returned to their normal values and patient was referred to the department of Nuclear Medicine for a radioactive iodine ablation therapy.
Conclusion: Concomitant papillary thyroid carcinoma and primary hyperparathyroidism is rare. It still remains controversial whether these two pathologies happen coincidental or are caused by specific risk factors or genetic changes.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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