Endocrine Abstracts

In this talk I aim to provide a helicopter view of clinical studies on maternal thyroid function and child neurodevelopment and use this to pinpoint out how different viewpoints on the results can help to interpret the clinical relevance of the currently available data and provide handles to make personal but informed clinical decisions. It is well-established that thyroid hormone plays an important role during early stages of fetal brain development. Thyroid hormone-dependent...

Rickets is the most common non-communicable disease in low and middle income countries and is re-emerging in countries such as the UK where it was once thought to be eradicated. Rickets is a bone disease which affects growing children and is caused by the undermineralisaton of the growth plate of long bones. Rickets can lead to osteomalacia, disabling bone deformities of the lower-limbs, stunting, increased fracture risk and in severe cases circulating bone mineral disturbance...

The relevance of carbohydrate metabolism studying in patients with Cushing disease (CD) and acromegaly can be explained by frequent occurrence of glucose metabolism disturbances on the one hand, and difficulties in glucose-lowering therapy in these patients on the other. The effectiveness of hyperglycaemia treatment may be reduced due to difficulties in remission/cure of the underlying disease, as well as to the use of specific drug-therapy, leading to hyperglycaemia. There is...