Endocrine Abstracts

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The T2-weighted characteristics of GH-secreting pituitary adenomas have recently received particular attention from the research community. It now appears that somatotropinomas can be divided into groups with different behavior according to their T2-weighted signal. T2-hypointense adenomas are generally smaller, invade the cavernous sinus less frequently and are responsible for higher levels of GH-hypersecretion (Fig. 1). Treatment with somatostatin analogues, both before and ...

Therapeutic response for medical therapy in hormonally functioning pituitary tumours is different in various types of tumours. While majority of prolactinomas respond well for medical therapy using dopamine agonists, in other tumours like somatotropinoma or corticotropinoma their response is significantly lower. In some case therapy resistance can occur. There are various factors determining the efficacy of medical therapy in patients harboring functioning pituitary adenomas. ...