Endocrine Abstracts

In the last 20 years, the incidence of thyroid cancer (TC) has more than doubled. Since 50% of the increase is related to papillary microcarcinomas (mPTC, <1 cm), it appears that an increased detection, due to the wide use of neck ultrasound (US), is the major factor driving this dramatic rise. Autoptic and histological studies after thyroidectomy (TX) show that 10 to 30% of adults harbor an undiagnosed mPTC. The disease-specific mortality of patients treated by s...

Thyroid cancer is one of the most rapidly increasing cancer diagnoses worldwide. Thyroid cancers exhibit the full range of cancer behavior from the relatively indolent occult papillary thyroid cancer to the uniformly aggressive and lethal undifferentiated thyroid cancers. Surgical resection is the principal treatment for thyroid cancer and there are several important areas of controversy in the surgical management of thyroid cancer. Some of these controversies have arisen due ...

In recent years, an increasing interest in an individualized approach for the care of patients with differentiated thyroid cancer has occurred. The cornerstone of individualized treatment is the existence of a proper risk stratification system that supports physicians’ options regarding the treatment and follow-up of patients. Considering that the initial risk stratification systems account for only about 15–20% of the variability in the outcome they are trying to pr...