ECE2017 Eposter Presentations: Diabetes, Obesity and Metabolism Obesity (81 abstracts)
Clinical and metabolic markers of X-syndrome
Irina Savasteeva 1 , Yana Navmenova 1 , Yulia Yarets 1 , Alena Makhlina 2 , Marina Kaplieva 2 , Tamara Yeudachkova 1 & Elena Vaschenko 1
1Republican Scientific and Practical Center for Radiation Medicine and Human Ecology, Gomel, Belarus; 2Gomel State Medical University, Gomel, Belarus.
We identified factors that significantly influenced the development of the X-syndrome. A significant influence on the development of X-syndrome have increase the level of total cholesterol (b=0.65; P=0.036; Exp (b) =1.92 (1.04÷3.54)). Increases the risk of X-syndrome increase the level of apo-B-protein (b=4.79; P=0.014; Exp (b) =12.69 (2.68÷54.41)). The increase in linear dimension of preperitonialy fat increased the risk of developing X-syndrome (b=1.14, P=0.036; Exp (b)=3.14 (1.08÷9.16)). By reducing the level of free thyroxine was a consistent trend of formation of X-syndrome (b=−0.25; P=0.09; Exp (b) =1.08 (0.57÷1.10)). When using the ROC analysis were obtained by the cut-off point, allowing to calculate the relative risk. The critical cut-off point for preperitonealny fat figure was more linear size 2.1 sm (P<0.02); total cholesterol – more than 6.36 mmol/l (P<0.02), apo-B-protein – more than 1.15 g/l (P<0.001), free thyroxine – less than 13.40 pmol/l (P<0.001). If the linear dimension preperitonealny fat more 2.1sm RR X-syndrome was 3.00 [0.87÷10.39]. When total cholesterol level of more than 6.36 mmol/l RR X-syndrome was 16.50 [2.05÷33.05]. When damage apo-B protein over 1.15 g/l RR X-syndrome was 22.00 [2.49÷94.44]. By reducing the thyroxine levels below 13.40 mmol/l RR X-syndrome was 13.00 [1.53÷110.51].
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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