Endocrine Abstracts

Purpose: To improve methods of plastic closure of wound defects in patients with diabetic foot syndrome using skin flaps on vascular pedicle of the perforating vessels.

Methods: The study involved patients with diabetes type 2 complicated with diabetic foot syndrome neuroischemic form. The study included 31 patients, 15 people in the study group and 16 people - the control group. Area wounds ranged from 3.8 to 21 cm². Cleansing the wounds was performed by ultrasonic cavitation. On the wound bandage with sorption-based antimicrobial composition of nanosized silica. Thus, the wound was purified for 2–3 days. On the third day, the wound was applied vacuum-assisted closure with a standard negative pressure of 125 mm Hg. The device was applied for 3–6 days. The number of colony-forming units for the success of the operation should be less than 10. Formed flap, which corresponds to the size and configuration of the defect on the foot.

Results: In the study group noted engraftment graft in 14 patients. Time of full engraftment and the healing of the wound defect in patients of the main group was 14±3 days in the control group healing ulcers - 51±10 days.

Conclusions: Improved techniques in the treatment of wound autodermoplastic defects in patients from diabetic foot syndrome, which is preparation wounds using an ultrasonic cavitation, vacuum bandage hardware. Using a split skin flap can effectively cover the bandage wounds, supporting the ability to save limbs and improve the quality of life.