ECE2017 Eposter Presentations: Adrenal and Neuroendocrine Tumours Endocrine tumours and neoplasia (50 abstracts)
The Department of Endocrinology and Diabetology of Hedi Chaker Hospital in Sfax, Sfax, Tunisia.
Introduction: Neuroendocrine tumors may develop in almost any organ. These types of tumors may present with giant and asymptomatic mass. We describe a case of a large non functional neuroendocrine tumor reported in the department of endocrinology and diabetology of Hedi Chaker hospital in Sfax-Tunisia in 2016.
Presentation of case: A 28 years old male presented with asthenia, gastric heaviness and epigastric pain. Further computerized tomography, a large mass (20 cm) near the stomach in the coeliomesenteric region has been demonstrated. Magnetic Resonance Imaging has showed the presence of a voluminous encapsulated mass with abundant vascularization and central necroses, measuring 18.5 cm×14.5 cm compressing the vascular structures. The dosage of methoxylated plasma derivatives was negative. The dosage of NSE was returned positive at 30.5 ng/l. The biopsy of the mass showed a histological and immunohistochemical aspect of a neuroendocrine tumor. The therapeutic decision was to start with exploratory laparotomy and tumor excision if possible. Because of the vascularized character and significant bleeding during the intervention, a surgical abstention was decided. The patient had two chemoembolization sessions with good tumor response. It is being evaluated for possible re-intervention.
Conclusion: The incidence of neuroendocrine tumors has been increasing during the last decade, underscoring the need to improve our understanding of their biology and behavior especially.