Endocrine Abstracts

In this debate I will make an overview of outcomes of NFPA patients with post-operative remnants, who were treated conservatively after surgery. In view of the high rates of tumor progression with consequent need for repeated surgery and radiation therapy, we propose the use of dopamine agonists in these patients. Recent data showing that preventive treatment with dopamine agonists significantly reduces the rate of tumor progression and the need for radiation therapy or additi...

Non-functioning pituitary adenomas (NFPA) are the second most common variant of pituitary tumors. They are presented by compression symptoms, hypopituitarism and in rec as incidental findings during brain imaging. When symptomatic, primary therapy for NFPAs is surgery most commonly by the trans-sphenoidal (TSS) approach. Medical therapy is not generally recommended in this setting, particularly when immediate decompression of the optic chiasm is needed. Despite the debulking e...