Endocrine Abstracts

31 year old lady was referred to the endocrine clinic by her GP in August 2008. She had 1 year history of galactorrhoea, 4 months history of irregular periods and intermittent short lived severe headache in the right temporal area without visual disturbance. Her investigation showed a prolactin level of 900 mmol/l, subsequent MRI scan confirmed the presence of right-sided pituitary adenoma of around 1 cm in size with evidence of recent haemorrhage in to it and normal other pituitary function. She was started on Cabergoline 0.25 mg twice a week in September 2008. Developed unpleasant psychological symptoms although multiple attempt were made to adjust the dose there was a ceiling of Cabergoline dose above which she experienced subtle symptom which meant full medical control was not possible. The tumour itself was slightly unusual in that it seemed to extend down through the floor of the pituitary into the sphenoid sinus through a bony defect with repeated evidence of haemorrhage in to it on follow up MRIs. Ongoing headache with intolerance to high dose dopamine agonist dictated surgical intervention. She underwent trans sphenoidal surgery in March 2014. Off dopamine agonist since and currently she is 35 weeks pregnant after spontaneous conception with minimal symptom during pregnancy.