Endocrine Abstracts

Auto-immune diseases are complex diseases, that occur as a result of the influence and interaction of multiple genes, (at least 20, could be more than 100). However, the critical feature of these diseases is that they only occur after exposure to an environmental trigger. As yet, most environmental triggers have not been identified.Most human autoimmune diseases have been shown to have an association with genes in the Major Histocompatibility Complex (MH...

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The neuroendocrine hypothalamus is located at the base of our brain and is important for controlling various physiologies, such as hunger, thirst, thermoregulation, and reproduction. Despite considerable knowledge about the hormones that regulate these physiologies and the circuits responsible for transmitting their cues, very little known about the developmental programs that govern hypothalamic formation the first place. Indeed, questions still remain about how individual hy...